MICROGLIA ARE NOT PROTECTIVE AGAINST CRYPTOCOCCAL MENINGITIS

Microglia are not protective against cryptococcal meningitis

Abstract Microglia provide protection against a range of brain infections including bacteria, viruses and parasites, but how these glial cells respond to fungal brain infections is Loaf Pan poorly understood.We investigated the role of microglia in the context of cryptococcal meningitis, the most common cause of fungal meningitis in humans.Using a

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Mitochondrial DNA variation in the endangered fish Dawkinsia tambraparniei (Actinopterygii: Cypriniformes: Cyprinidae) from southern Western Ghats, India

Background.Dawkinsia tambraparniei (Silas, 1954) is confined to an area not exceeding 100 km2 within a single watershed—the Tamiraparani River, southern Western Ghats, India.Its populations have recently declined, earning the fish the endangered status.For effective conservation efforts it is important to determine the levels of genetic v

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Primary Impacts of the Fungal Toxin Sporidesmin on HepG2 Cells: Altered Cell Adhesion without Oxidative Stress or Cell Death

The fungal metabolite sporidesmin is responsible for severe necrotizing inflammation of biliary tract and liver of livestock grazing on pasture containing spores of Pithomyces chartarum that synthesizes the toxin.The toxin is secreted into bile causing the erosion of the biliary epithelium accompanied by inflammation and damage to surrounding tissu

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